Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney

Estrogen deficiency compromised the β 2 AR-Gs/Gi coupling: implications for arrhythmia and cardiac injury

Identification of expression and function of the glucagon-like peptide-1 receptor in colonic smooth muscle

TNF-α impairs EP4 signaling through the association of TRAF2-GRK2 in primary fibroblast-like synoviocytes

Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor

The GABA B receptor mediates neuroprotection by coupling to G 13

Biased antagonism of CXCR4 avoids antagonist tolerance

VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1

The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors

Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling

Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

Small Molecule Inhibitors Targeting Gα i 2 Protein Attenuate Migration of Cancer Cells

GPER mediates estrogen cardioprotection against epinephrine-induced stress

Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport

Impaired Trafficking of β1 Subunits Inhibits BK Channels in Cerebral Arteries of Hypertensive Rats

Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth

Rab11 activation by Ik2 kinase is required for dendrite pruning in Drosophila sensory neurons

Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex

Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic Cells

Interferon-β-induced miR-1 alleviates toxic protein accumulation by controlling autophagy