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Anti- KIT(V560D) Mouse Monoclonal Antibody

价格¥4800.00
品牌NewEast Biosciences   
产地中国 武汉
货号26281
规格100ul
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  • KIT(V560D) [26281]
    [100ul]

    Catalog Number:  26281
    Gene Symbol:  C-Kit; CD117; KIT; PBT; SCFR
    Description:   Anti KIT(V560D) Mouse Monoclonal Antibody
    Background:   Tyrosine-protein kinase Kit, also known as proto-oncogene c-Kit or CD117 or Mast/stem cell growth factor receptor (SCFR), is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene. Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.
    Immunogen:   A synthetic peptide from the internal region of KIT which includes the mutation of V560D, human origin.
    Applications:   ELISA, WB
    Recommended Dilutions:   
    ELISA: 1:1000-1:5000 
    WB: 1:500-1:1000
    Concentration:   1 mg/ml
    Host:   Mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Recognizes V560D mutant, but not wild-type KIT of vertebrates.
    Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
     
    Western blot:  
    Western blot analysis of recombinant KIT(V560D) and wildtype proteins. Purified His-tagged KIT(V560D) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti KIT(V560D) monoclonal antibody (Cat. #26281).

     

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