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| 价格 | ￥4800.00 |
| 品牌 | NewEast Biosciences  |
| 产地 | 中国 武汉 |
| 货号 | 26214 |
| 规格 | 100ul |
| 说明书 | 说明书下载 |
PIK3CA(Q546R) [26214]
[100ul]
| Catalog Number: 26214 |
| Gene Symbol: PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha |
| Description: Anti PIK3CA(Q546R) Mouse Monoclonal Antibody |
| Background: Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found in the pathogenesis of several cancers, including colon cancer, gliomas, gastric cancer, breast cancer, endometrial cancer, and lung cancer. |
| Immunogen: A synthetic peptide from the internal region of PIK3CA which includes the mutation of Q546R, human origin. |
| Applications: WB |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:2000 |
| Concentration: 1 mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes Q546R mutant, but not wild-type PIK3CA of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Western blot: |
 |
Western blot analysis of recombinant PIK3CA(Q546R) and wildtype proteins. Purified His-tagged PIK3CA(Q546R) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti PIK3CA(Q546R) monoclonal antibody (Cat. #26214). |
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