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Anti- ATM(R3008H) Mouse Monoclonal Antibody

价格¥4800.00
品牌NewEast Biosciences   
产地中国 武汉
货号26140
规格100ul
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  • ATM(R3008H) [26140]
    [100 µL]

     

    Catalog Number:  26140
    Gene Symbol:  ATM
    Description:   Anti ATM(R3008H) Mouse Monoclonal Antibody
    Background:   Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers.
    Immunogen:   A synthetic peptide from the internal region of ATM which includes the mutation of R3008H, human origin.
    Applications:   ELISA, WB, IHC
    Recommended Dilutions:   
    ELISA: 1:1000-1:5000 
    WB: 1:100-1:1000 
    IHC: 1:50-1:500
    Concentration:   1 mg/ml
    Host:   Mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Recognizes ATM(R3008H), but not wild type ATM protein from vertebrates.
    Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
     
    Western blot:  
    Western blot analysis of recombinant ATM(R3008H) and wildtype proteins. Purified His-tagged ATM(R3008H) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti ATM(R3008H) mouse monoclonal antibody (Cat. #26140).

     

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    26141 Anti ATM(F858L) Mouse Monoclonal Antibody  100 μL  ¥4800
    26142 Anti ATM(Q2442P) Mouse Monoclonal Antibody  100 μL  ¥4800 
    26140 Anti ATM(R3008H) Mouse Monoclonal Antibody  100 μL  ¥4800
    26143 Anti ATM(R2443Q) Mouse Monoclonal Antibody  100 μL  ¥4800

     

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