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Anti- Active Rab5 Mouse Monoclonal Antibody

价格¥4800.00
品牌NewEast Biosciences    
产地中国 武汉
货号26911
规格30μl
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  • Active Rab5 GTP [26911]
    [30 µL]

     

    Catalog Number:  26911
    Gene Symbol:  RAB5
    Description:   Anti Active Rab5 Mouse Monoclonal Antibody
    Background:   Rab5 is a member of Rab-family GTPases. Rab5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway.
    Immunogen:   Recombinant full length protein of active Gao
    Applications:   IP, IHC
    Recommended Dilutions:   1 µg for ~2 mg total cellular proteins for IP 
    1:100 dilution for IHC
    Concentration:   1 mg/ml
    Host:   mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   IgG1
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Anti-active Rab5 antibody recognizes active Rab5 proteins of vertebrates.
    Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
     
    Immunoprecipitation/Western blot:  
    Rab5 activation assay. Purified full-length Rab5A proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti active Rab5 monoclonal antibody (Cat. No. 26911). Immunoblot was with an anti Rab5 polyclonal antibody (Cat. No. 21151).

     

    Related Products
    Catalog# Name Size Price
    83701 Rab5 Activation Assay Kit  20 assays  ¥6800
    81301 Rab5A Activation Assay Kit  20 assays ¥6800
    83401 Rab5B Activation Assay Kit  20 assays  ¥6800
    83501 Rab5C Activation Assay Kit  20 assays  ¥6800
    26911 Active Rab GTP Monoclonal Antibody  30 μL  ¥4800
    26016 Anti Rab5 Mouse Monoclonal Antibody  100 μL  ¥2800   
    21151 Anti Rab5 Rabbit Polyclonal Antibody  100 μL  ¥2600  
    21036 Anti Rab5A Rabbit Polyclonal Antibody  100 μL  ¥2600    
    21037 Anti Rab5B Rabbit Polyclonal Antibody  100 μL  ¥2600   
    21038 Anti Rab5C Rabbit Polyclonal Antibody  100 μL  ¥2600 

     

     

    Publications:
    1.  VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
        Hepatology Volume 61, Issue 1, pages 361–374, January 2015
    2.  Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance
        Endocrinology. 2014 Sep;155(9):3315-28

     

     

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