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价格 | ¥1600.00 |
品牌 | NewEastBio |
产地 | 中国 武汉 |
货号 | 21021 |
规格 | 100μl |
说明书 | 说明书下载 |
Ras [21021]
[100 µL]
Catalog Number: 21021 |
Gene Symbol: RAS |
Description: Anti Ras Rabbit Polyclonal Antibody |
Background: Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs). |
Immunogen: A synthetic peptide from the C-terminus of Ras |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA 1:100-1:5000 WB 1:100-1:2000 IHC 1:100-1:1000 |
Concentration: 0.2 mg/ml |
Host: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Isotype: IgG |
Purity: Purified from serum |
Storage buffer: |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Ras antibody recognizes H-Ras, N-Ras and K-Ras from vertebrates. |
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Western blot: |
HEK-293T whole-cell lysate was used for Western blot with anti Ras polyclonal antibody (cat # 21021). |
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Publications: |
1. DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model Gene Therapy 21, 888-896 (October 2014) |